Alternative names:

TNFSF18;AITRL;TL6;hGITRL;GITR Ligand

Description:

Recombinant human GITR Ligand protein with N-terminal mouse Fc and C-terminal 6×His tag

Background:

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.

Molecular characterization:

mFc(Pro99-Lys330) GITR Ligand(Gln50-Ser177) 6×His

Molecular weight:

The protein has a predicted molecular mass of 46-53 kDa after removal of the signal peptide.

Tag:

N-Mouse Fc and C-6×His Tag

Expression host:

HEK293

Target:

GITR Ligand

Purity:

The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Formulation / Reconstitution:

Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.

Storage:

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

More info:

Email info@sobekbio.com

Orders:

Email orders@sobekbio.com