Background:

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

NPM1; NPM; Nucleophosmin; NPM; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Numatrin

Species reactivity:

Human,Mouse,Rat,Bovine,Pig,Rabbit

Host:

Mouse

Isotype:

IgG

Immunogen:

Purified recombinant human B23 protein fragments expressed in E.coli.

Concentration:

1 mg/ml

Molecular weight:

N/A

Applications:

WB, IF, ICC

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

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