Background:

Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways . Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. COVID-19 antibodies can be produced by a host immune system following exposure to SARS-CoV-2. IgG and IgM antibodies are also known as immunoglobulins IgG and IgM, respectively, and are among the antibody isotypes produced by vertebrate immune systems. 

Classification:

Secondary antibody

Alternative names:

SARS-CoV-2 Nucleoprotein , 2019-nCoV Nucleoprotein, Covid-19 Nucleoprotein

Species reactivity:

Covid-19

Host:

Mouse

Isotype:

IgG

Immunogen:

The recombinant SARS-CoV-2 (2019-nCoV) N Protein

Concentration:

2mg/mL

Molecular weight:

Applications:

WB,ELISA

Storage:

-20°C for 1 year

More info:

Email: info@sobekbio.com

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