Background:

ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein (ADP ribosylation factor guanine nucleotide exchange factor 2) encoded by ARFGEF2 is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition.

Classification:

Primary antibody

Alternative names:

ARFGEF2; ARFGEP2; BIG2; Brefeldin A-inhibited guanine nucleotide-exchange protein 2; Brefeldin A-inhibited GEP 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ARFGEF2. AA range:1491-1540

Concentration:

1 mg/ml

Molecular weight:

202038

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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