Background:

SFN (Stratifin) is a Protein Coding gene. Diseases associated with SFN include pancreatic ductal adenocarcinoma and limbal stem cell deficiency. Among its related pathways are Gene Expression and Signaling by GPCR. GO annotations related to this gene include protein kinase binding and phosphoprotein binding. An important paralog of this gene is YWHAZ. dapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. 53-regulated inhibitor of G2/M progression.

Classification:

Primary antibody

Alternative names:

SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human SFN. AA range:41-90

Concentration:

1 mg/ml

Molecular weight:

27774

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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